Wallach teaches courses in Laboratory Biomethods, Pharmacology and Toxicology Laboratory Techniques, Psychopharmacology, Pathology, Simulated Physiology Labs and Toxicology. Wallach also has an appointment to the Substance Use Disorders Institute where he is interested in medical cannabis and curriculum development for substance use disorder education. Wallach’s research focuses on the analytical and pharmacological characterizations of psychoactive drugs focusing on synthetic psychoactive drugs (SPDs) and “legal highs”. Wallach also conducts research in drug development for several therapeutic areas including neuropathic pain, neurodegenerative disease, depression, and cancer. This work includes investigations of structure activity relationships, drug tolerability, target selectivity and multi-target drug design, and biased ligand development.